Increased detection of interleukin-5 in sputum by addition of protease inhibitors

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Increased detection of interleukin-5 in sputum by addition of protease inhibitors.

The measurement of interleukin (IL)-5 in sputum is problematic, with interfering factors affecting immunoassay. The authors investigated whether sputum proteases could be acting as interfering factors by studying the effect of protease inhibitors (PI) on sputum IL-5 measurement. Induced sputa from 20 subjects with asthma were divided into aliquots, processed with and without protease inhibitors...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2001

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.01.00098501